所属类别： 140毫克/片 30片/瓶
包装规格： 140毫克/片 30片/瓶
生产厂家英文名：Bristol-Myers Squibb GmbH & Co. KGaA
原产地英文商品名：Sprycel 140mg/Filmtabletten 30Filmtabletten
中文参考商品译名：Sprycel薄膜片 140毫克/片 30片/瓶
SprycelGeneric Name: dasatinib (da SAT in ib)Brand Names: Sprycel———————————————————————What is Sprycel?Sprycel (dasatinib) is a cancer medication that slows the growth and spread of cancer cells in the body.Sprycel is used to treat chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) when other cancer treatments have not been effective.Sprycel may also be used for purposes not listed in this medication guide.———————————————————————Important information about SprycelDo not use Sprycel if you are pregnant. It could harm the unborn baby. Use birth control to prevent pregnancy while you are receiving Sprycel, whether you are a man or a woman.Sprycel use by either parent may cause birth defects.Before taking Sprycel, tell your doctor if you have liver disease, low levels of potassium or magnesium in your blood, heart disease or a heart rhythm disorder, or if you have a personal or family history of "Long QT syndrome."Do not crush, chew, or break a Sprycel tablet. Swallow it whole.Breaking the pill may cause too much of the drug to be released at one time. There are many other drugs that can interact with Sprycel.Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.Sprycel can lower blood cells that help your body fight infections.This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly.Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.———————————————————————Before taking SprycelYou should not use Sprycel if:you have not first received a medication called imatinib (Gleevec); orif you are pregnant or planning to become pregnant during treatment with Sprycel.To make sure you can safely take Sprycel, tell your doctor if you have any of these other conditions:liver disease;low levels of potassium or magnesium in your blood;heart disease or a heart rhythm disorder; ora personal or family history of "Long QT syndrome."FDA pregnancy category D. Do not use Sprycel if you are pregnant. It could harm the unborn baby. Tell your doctor if you become pregnant during treatment. Use birth control to prevent pregnancy while you are receiving Sprycel, whether you are a man or a woman. Sprycel use by either parent may cause birth defects. A man taking Sprycel should use a condom during any sexual activity. It is not known whether dasatinib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while taking Sprycel. This medication may affect fertility (your ability to have children), whether you are a man or a woman.Sprycel tablets contain lactose. Talk to your doctor before using this medication if you are lactose-intolerant.———————————————————————How should I take Sprycel?Take Sprycel exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.This medicine is usually taken once in the morning and once in the evening. Follow your doctor's instructions. You may take the medication with or without food.Your doctor may occasionally change your dose to make sure you get the best results.Take Sprycel tablets with a full glass of water. Do not crush, chew, or break a Sprycel tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. Do not use a pill that has been accidentally broken. Dasatinib from a crushed or broken Sprycel tablet can be dangerous if it gets in your eyes, mouth, or nose, or on your skin. If this occurs, wash your skin withsoap and water or rinse your eyes with water. Ask your doctor or pharmacist how to safely handle and dispose of a broken tablet.Sprycel can lower blood cells that help your body fight infections.This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly.Store Sprycel at room temperature away from moisture and heat.———————————————————————What happens if I miss a dose?Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.———————————————————————What happens if I overdose?Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.——————————————————————–What should I avoid while taking Sprycel?Avoid taking an antacid within 2 hours before or 2 hours after you take Sprycel. Use only the type of antacid your doctor recommends.Some antacids can make it harder for your body to absorb Sprycel.Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.Grapefruit and grapefruit juice may interact with Sprycel and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.———————————————————————Sprycel side effectsGet emergency medical help if you have any of these signs of an allergic reaction to Sprycel: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;easy bruising, unusual bleeding (nose, mouth, vagina, or rectum),purple or red pinpoint spots under your skin;fever, chills, body aches, flu symptoms, sores in your mouth and throat;black, bloody, or tarry stools;coughing up blood or vomit that looks like coffee grounds; orswelling in your hands, ankles, or feet.Less serious Sprycel side effects may include:headache;tired feeling;nausea, diarrhea; ormild skin rash;This is not a complete list of side effects and others may occur.Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.———————————————————————What other drugs will affect Sprycel?Tell your doctor about all other medicines you use, especially:alfentanil (Alfenta), fentanyl (Actiq, Duragesic);bosentan (Tracleer);conivaptan (Vaprisol);cyclosporine (Gengraf, Neoral, Sandimmune);dexamethasone (Decadron, Hexadrol);ergotamine (Ergomar, Cafergot, Migergot);imatinib (Gleevec);isoniazid (for treating tuberculosis);pimozide (Orap);rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), orrifapentine (Priftin);St. John's wort;an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);an antidepressant such as nefazodone;antifungal medication such as clotrimazole (Mycelex Troche), itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), or voriconazole (Vfend);phenobarbital (Solfoton) and other barbiturates;a blood thinner such as warfarin (Coumadin);heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine(Rescriptor), efavirenz (Sustiva), etravirine (Intelence), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), saquinavir (Invirase), or ritonavir (Kaletra, Norvir);medicines to treat narcolepsy, such as armodafanil (Nuvigil) or modafanil (Progivil);medication used to prevent blood clots, such as bivalirudin(Angiomax), clopidogrel (Plavix), dalteparin (Fragmin), dipyridamole(Persantine, Aggrenox), enoxaparin (Lovenox), fondaparinux (Arixtra), lepirudin (Refludan), ticlopidine (Ticlid);medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf);seizure medication such as carbamazepine (Carbatrol, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline); orstomach acid reducers such as cimetidine (Tagamet), esomeprazole (Nexium), famotidine (Pepcid), lansoprazole (Prevacid), nizatidine (Axid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), rabeprazole (Aciphex), or ranitidine (Zantac).This list is not complete and there are many other drugs that can interact with Sprycel. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.———————————————————————Where can I get more information?Your pharmacist can provide more information about Sprycel.Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as asupplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.
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