索坦胶囊SUTENT 50mg Capsules(Sunitinib Malate )

 药店国别:

产地国家:意大利

处方药:是

所属类别: 50毫克/胶囊 14胶囊/瓶

包装规格: 50毫克/胶囊 14胶囊/瓶

计价单位:瓶

生产厂家中文参考译名:

生产厂家英文名:pfizer

原产地英文商品名:SUTENT 50mg/cap 14caps/bottle

原产地英文药品名:SUNITINIB MALATE

中文参考商品译名:索坦 50毫克/胶囊 14胶囊/瓶

中文参考药品译名:苹果酸舒尼替尼

曾用名:

简介:

部分中文索坦信息资料(仅供参考)

【商品名】

索坦

【通用名】

苹果酸舒尼替尼

【英文名】

sunitinib malate(Sutent)

【用法】

每天4粒,一次顿服4粒,服用4周后需停药观察2周后继续服用

【疗程】

6周/疗程

【适应症】

胃肠道间质瘤、肾癌

【份子结构名】

苹果酸舒尼替尼

【生产厂家】

Pfizer辉瑞公司

【适应症】

除了胃肠道间质肿瘤,抑制晚期肾细胞癌,现在临床证明还可以治疗非小细胞肺癌,治疗肝细胞癌.舒尼替尼—治疗肾癌、胃肠间质瘤舒尼替尼(sunitinibmalate)是由美国辉瑞公司开发的一种口服小分子多靶点酪氨酸激酶受体抑制剂。分别于2006年1月和2007年1月由美国FDA和欧洲EMEA批准上市,商品名为Sutent,为口服胶囊制剂,用于治疗胃肠道间质肿瘤(GIST)和晚期肾细胞瘤。

舒尼替尼是一种能够抑制多种酪氨酸激酶受体的小分子化合物,它可以通过抑制血管内皮生长因子受体、血小板衍生生长因子受体、干细胞因子受体、Fms-样酪氨酸激酶一3、集落刺激因子受体I型和神经胶质细胞系衍生神经营养因子受体的酪氨酸激酶受体的活性,阻断肿瘤细胞生长的血液和营养供应,从而产生抗血管生成和抗肿瘤作用,此外,Sutent还可以直接杀伤肿瘤细胞。

Ⅲ期临床试验结果证实,与使用干扰素相比,晚期/转移性肾细胞癌(MRCC)患者使用Sutent,病情不恶化患者的存活时间由5个月增加到11个月。口服Sutent可能会出现乏力、虚弱、恶心、消化不良、腹泻或口腔黏膜炎、中性粒细胞减少、血小板减少以及皮炎、皮肤脱色或毛发褪色等轻中度不良反应,患者能够很好地耐受。目前该药已经得到我国药监部门批准上市,并于国内开展舒尼替尼(Sutent)治疗转移性肾癌的多中心开放性Ⅳ期临床试验。

苹果酸舒尼替尼英文版说明书

Sutent Sunitinib MalateBrand Name: Sutent 12.5mg、25mg、50mgStrength:12.5mg、25mg、50mgContents: Sunitinib Malate 12.5mg、25mg、50mgForm:CapsulesManufacturer: Pfizer Italia S.R.LCountry Of Origin: ItalySUTENTSunitinib by PfizerSutent (also known by the generic name Sunitinib) is amedication that is used to slow the growth and spread of cancer cells in thebody. It is principally used to treat kidney and intestinal cancers. Sutent is areceptor protein-tyrosine kinase inhibitor and also an angiogenesis inhibitor,which inhibits the actions of vascular endothelial growth factor (alsoabbreviated VEGF).Cancer cells have abnormal rates of growth and multiply atates that are different than normal cells. Sutent interferes with the abilityof cancer cells to multiply and grow, thereby reducing the total number of cellsand helping to stop their spread throughout the body.What are the side effectsof using Sutent (Sunitinib)?Side effects associated with the use of Sutent mayinclude mild nausea, vomiting, diarrhea, constipation or loss of appetite,headache, joint or muscle pain, changes in hair color or texture, and strangetastes in the mouth.More severe side effects are possible and may includeshortness of breath, significant weakness and feeling faint, swelling in limbsor face, chest pain or pressure, fatigue, numbness or tingly feeling anywhere inthe body, confusion, bruising, white patches or sores in and on the mouth,vomiting or coughing of blood or material that looks like wet coffee grounds,and redness or peeling rash on the hands or soles of your feet. Contact yourdoctor immediately if you experience these or any other unusual symptoms whileusing this medicine.Allergic reactions are possible when receiving this drug andinclude a sudden rash, itchiness or swelling of the skin, mouth, or throat, anddifficulty breathing. If you suspect an allergic reaction while taking Sutent,seek emergency medical care.What precautions are advised when using Sutent(Sunitinib)?Receiving Sutent may weaken your body’s immune system, so avoidpeople who have colds, the flu, or other infections.There are various drugs thatcan interfere with the way Taxotere works in your body including certainanti-fungals and antibiotics, corticosteroids, other cancermedicines,immunosuppressants, seizure medicines, and any herbal or other nutritionalsupplements you may be taking. Discuss these with your doctor.Women who arepregnant or nursing should not take Sunitinib unless specifically prescribed bytheir doctor. Women taking this medicine are advised against becoming pregnantbecause this drug could harm an unborn baby.What happens with an overdose ofSutent (Sunitinib)?Overdoses with Sutent may include chills, tremors, stomachpain, weakness, or any of the severe side effects listed previously. Contact adoctor right away if you suspect you have received an overdose of thisdrug.Sutent Intake GuidelinesPatients are recommended to ask their personalhealthcare provider to explain them exactly how they should take Sutent. It isrecommended to listen and remember all of the doctor’s instructions. If thepatients do not understand one or more of the doctor’s recommendations theyshould ask him again or contact a pharmacist for more information.Every dose ofSutent must be taken with at least two quarts of fluid in order to avoid anupset stomach. Persons who are under treatment with this medicine should avoiddrinking, should have an equilibrate diet and often wash their hands. Patientswho are taking this medicine have a high risk of infection this is why it isrecommended to avoid crowded places, people with colds. In order to reduce thesymptoms, patients are recommended to take anti-nausea drugs and to eat smalland frequent meals.

我们希望人人都能吃的起药,看得起病! 我们希望让患者有权利选择自己经济能力范围内的药! 我们希望给国人提供一个能了解药品常识的平台,不再一无所知! 我们经过一年多时间反复深入的分析、研究,咨询了很多医学专家,药学专家,对比了近2000种重大疾病用药,总结了数百万字的药品知识。 我们建立医生China,是全国首个药品知识型公益社区。 www.yschn.com-医生China
药品价格查询,专业药品查询网站,药品说明书查询,药品比价 » 索坦胶囊SUTENT 50mg Capsules(Sunitinib Malate )

提供最优质的资源集合

立即查看 了解详情